August 2025#

This is the fourth issue of our new monthly newsletter, designed to keep you up to date on the latest SAMSON developments, new features, collaborations, and upcoming events.

Power Fetcher#

SAMSON's Structure Fetcher (Home > Fetch) has been completely redesigned and significantly expanded. You can now download structures from the RCSB Protein Data Bank, the AlphaFold Protein Structure Database, the ESM Metagenomic Atlas, PubChem, and the Crystallography Open Database, directly from SAMSON. You can now also convert IUPAC and SMILES into 3D structures that are automatically added to the document.

Fetcher

Extensions Updates#

Enhanced Features#

Many SAMSON extensions were updated this month:

SAMSON AI now embeds GPT-5 for all users. Professional and Enterprise users also benefit from advanced AI commands for literature, scripting and modeling.
Adenita: this popular SAMSON extension for modeling and visualizing DNA nanostructures is now open source! Feel free to contribute!
3D-SNFG visualization for glycans: Now supports path-tracing with Cycles, the integrated renderer from Blender (Visualization > Trace).
Structure Validation: Handles more non-standard residue aliases (e.g., from CpHMD).
Pathlines: Now supports transparency, path-tracing, and exposes new functionality.
Python Scripting: New functionality to fetch structures from data banks (SAMSON.fetch()) and select nodes in SAMSON (SAMSON.select()).

Bug Fixes#

We've resolved issues across several extensions, including GROMACS Wizard and OpenMM Wizard, ensuring smoother performance.

Documentation Updates#

A new tutorial is available to learn how to AlphaFold 2, Boltz-2 and Chai-1x directly from SAMSON: Predict Biomolecular Structures.

Explore more on our Tutorials Page.

Webinar Recording#

Missed our Summer webinar introducing SAMSON 2025 R1 and R2? Watch it on YouTube .

Upcoming Events#

Stephane Redon, CEO of OneAngstrom, will be introducing SAMSON in the Seminar on Digitalisation and Automation in Chemistry at FHNW in Muttenz, Switzerland (September 8-12, 2025).

Coming Soon: SAMSON 2025 R3#

We're preparing SAMSON 2025 R3! Your feedback is vital - let us know your feature requests.

Thank you for being part of our growing community!